Chronic exposure in vivo to thyrotropin receptor stimulating monoclonal antibodies sustains high thyroxine levels and thyroid hyperplasia in thyroid autoimmunity-prone HLA-DRB1*0301 transgenic mice

We have examined the induction of autoimmunity and the maintenance of sustained hyperthyroidism in autoimmunity-prone human leucocyte antigen (HLA) DR3 transgenic non-obese diabetic (NOD) mice following chronic stimulation of the thyrotropin receptor (TSHR) by monoclonal thyroid-stimulating autoanti...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Flynn, Jeffrey C, Gilbert, Jacqueline A, Meroueh, Chady, Snower, Daniel P, David, Chella S, Kong, Yi-chi M, Paul Banga, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
Soggetti:
Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265995/
https://ncbi.nlm.nih.gov/pubmed/17535305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02635.x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi