Superiority of thyroid peroxidase DNA over protein immunization in replicating human thyroid autoimmunity in HLA-DRB1*0301 (DR3) transgenic mice

Murine experimental autoimmune thyroiditis (EAT), characterized by thyroid destruction after immunization with thyroglobulin (Tg), has long been a useful model of organ-specific autoimmune disease. More recently, porcine thyroid peroxidase (pTPO) has also been shown to induce thyroiditis, but these...

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Autori principali: FLYNN, J C, GARDAS, A, WAN, Q, GORA, M, ALSHARABI, G, WEI, W Z, GIRALDO, A A, DAVID, C S, Kong, Y M, Banga, J P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2004
Soggetti:
Animal Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809151/
https://ncbi.nlm.nih.gov/pubmed/15320899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02553.x
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