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CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor

The chemokine receptor CXCR3 is critical for the function of activated T cells. We studied the molecular mechanisms of CXCR3 signalling. The addition of CXCR3 ligands to normal human T cells expressing CXCR3 led to the tyrosine phosphorylation of multiple proteins. Addition of the same ligands to Ju...

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Autori principali: Dar, Wasim A, Knechtle, Stuart J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265907/
https://ncbi.nlm.nih.gov/pubmed/17250586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02534.x
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