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On a key postulate of T-cell receptor restrictive function: the V-gene loci act as a single pool encoding recognition of the polymorphic alleles of the species major histocompatibility complex

The proposition that single Vα or Vβ gene segments specify the recognition of the allele-specific determinants expressed on the major histocompatibility complex-encoded restricting elements of the species has as its consequence a totally different picture of the functioning of the T-cell receptor. T...

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Dettagli Bibliografici
Autore principale: Cohn, Melvin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Inc 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265876/
https://ncbi.nlm.nih.gov/pubmed/17233741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02501.x
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