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Major histocompatibility complex-restricted self recognition. A monoclonal anti-I-Ak reagent blocks helper T cell recognition of self major histocompatibility complex determinants

The functional role of cell surface Ia antigens has been studied for in vitro antibody responses, using as a probe the ability of anti-Ia reagents to inhibit these responses. A hybridoma monoclonal anti-Ia reagent specific for a product of I-Ak (Ia.17) profoundly inhibited in vitro antibody response...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1980
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186014/
https://ncbi.nlm.nih.gov/pubmed/6161203
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