Quantification of Bax/Bcl-2 ratios in peripheral blood lymphocytes, monocytes and granulocytes and their relation to susceptibility to anti-Fas (anti-CD95)-induced apoptosis

Neutrophils have the shortest half-life among circulating leucocytes and rapidly undergo apoptosis in vitro. The homologous Bcl-2 and Bax proteins have opposing effects, with Bcl-2 extending cellular survival and Bax promoting cell death following an apoptotic stimulus. We determined Bcl-2 to Bax ex...

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Detalhes bibliográficos
Main Authors: VAN DER VLIET, H J J, WEVER, P C, VAN DIEPEN, F N J, YONG, S-L, BERGE, I J M TEN
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265491/
https://ncbi.nlm.nih.gov/pubmed/9367420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.1997.tb08335.x
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