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New Insights into Human Nondisjunction of Chromosome 21 in Oocytes
Nondisjunction of chromosome 21 is the leading cause of Down syndrome. Two risk factors for maternal nondisjunction of chromosome 21 are increased maternal age and altered recombination. In order to provide further insight on mechanisms underlying nondisjunction, we examined the association between...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265487/ https://ncbi.nlm.nih.gov/pubmed/18369452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000033 |
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