The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

MMSET, identified by its fusion to the IgH locus in t(4;14)-associated multiple myeloma, possesses domains found within chromatin regulators, including the SET domain. MMSET protein is overexpressed and highly associated with chromatin in myeloma cell lines carrying t(4;14). MMSET possesses methyltr...

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Detalhes bibliográficos
Main Authors: Marango, Jotin, Shimoyama, Manabu, Nishio, Hitomi, Meyer, Julia A., Min, Dong-Joon, Sirulnik, Andres, Martinez-Martinez, Yolanda, Chesi, Marta, Bergsagel, P. Leif, Zhou, Ming-Ming, Waxman, Samuel, Leibovitch, Boris A., Walsh, Martin J., Licht, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265454/
https://ncbi.nlm.nih.gov/pubmed/18156491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-092122
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