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The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor
MMSET, identified by its fusion to the IgH locus in t(4;14)-associated multiple myeloma, possesses domains found within chromatin regulators, including the SET domain. MMSET protein is overexpressed and highly associated with chromatin in myeloma cell lines carrying t(4;14). MMSET possesses methyltr...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265454/ https://ncbi.nlm.nih.gov/pubmed/18156491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-092122 |
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