Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

Multiple myeloma (MM) is a B-lineage malignancy characterized by diverse genetic subtypes and clinical outcomes. The recurrent immunoglobulin heavy chain (IgH) switch translocation, t(4;14)(p16;q32), is associated with poor outcome, though the mechanism is unclear. Quantitative reverse-transcription...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Keats, Jonathan J., Maxwell, Christopher A., Taylor, Brian J., Hendzel, Michael J., Chesi, Marta, Bergsagel, P. Leif, Larratt, Loree M., Mant, Michael J., Reiman, Tony, Belch, Andrew R., Pilarski, Linda M.
Format: Artigo
Langue:Inglês
Publié: © 2005 by The American Society of Hematology 2005
Sujets:
Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895072/
https://ncbi.nlm.nih.gov/pubmed/15677557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3704
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