Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

Multiple myeloma (MM) is a B-lineage malignancy characterized by diverse genetic subtypes and clinical outcomes. The recurrent immunoglobulin heavy chain (IgH) switch translocation, t(4;14)(p16;q32), is associated with poor outcome, though the mechanism is unclear. Quantitative reverse-transcription...

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Main Authors: Keats, Jonathan J., Maxwell, Christopher A., Taylor, Brian J., Hendzel, Michael J., Chesi, Marta, Bergsagel, P. Leif, Larratt, Loree M., Mant, Michael J., Reiman, Tony, Belch, Andrew R., Pilarski, Linda M.
Format: Artigo
Jezik:Inglês
Izdano: © 2005 by The American Society of Hematology 2005
Teme:
Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895072/
https://ncbi.nlm.nih.gov/pubmed/15677557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3704
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