Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

Multiple myeloma (MM) is a B-lineage malignancy characterized by diverse genetic subtypes and clinical outcomes. The recurrent immunoglobulin heavy chain (IgH) switch translocation, t(4;14)(p16;q32), is associated with poor outcome, though the mechanism is unclear. Quantitative reverse-transcription...

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Autores principales: Keats, Jonathan J., Maxwell, Christopher A., Taylor, Brian J., Hendzel, Michael J., Chesi, Marta, Bergsagel, P. Leif, Larratt, Loree M., Mant, Michael J., Reiman, Tony, Belch, Andrew R., Pilarski, Linda M.
Formato: Artigo
Lenguaje:Inglês
Publicado: © 2005 by The American Society of Hematology 2005
Materias:
Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895072/
https://ncbi.nlm.nih.gov/pubmed/15677557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3704
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