HTLV-1 Integration into Transcriptionally Active Genomic Regions Is Associated with Proviral Expression and with HAM/TSP

Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in ∼5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people, even at the same proviral load (proportion of infected mononuclear cells in the circulation)....

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Bibliografische gegevens
Hoofdauteurs: Meekings, Kiran N., Leipzig, Jeremy, Bushman, Frederic D., Taylor, Graham P., Bangham, Charles R. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2008
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265437/
https://ncbi.nlm.nih.gov/pubmed/18369476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000027
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