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HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP

BACKGROUND: HTLV-1 causes proliferation of clonal populations of infected T cells in vivo, each clone defined by a unique proviral integration site in the host genome. The proviral load is strongly correlated with odds of the inflammatory disease HTLV-1-associated myelopathy/tropical spastic parapar...

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Autors principals: Niederer, Heather A, Laydon, Daniel J, Melamed, Anat, Elemans, Marjet, Asquith, Becca, Matsuoka, Masao, Bangham, Charles RM
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192323/
https://ncbi.nlm.nih.gov/pubmed/25270762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-172
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