The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma

Adult T-cell leukemia/lymphoma (ATL) occurs in ∼5% of human T-lymphotropic virus type 1 (HTLV-1)–infected individuals and is conventionally thought to be a monoclonal disease in which a single HTLV-1(+) T-cell clone progressively outcompetes others and undergoes malignant transformation. Here, using...

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Detalhes bibliográficos
Main Authors: Cook, Lucy B., Melamed, Anat, Niederer, Heather, Valganon, Mikel, Laydon, Daniel, Foroni, Letizia, Taylor, Graham P., Matsuoka, Masao, Bangham, Charles R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064332/
https://ncbi.nlm.nih.gov/pubmed/24735963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-553602
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