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C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging
Inclusions in the brain containing α-synuclein are the pathological hallmark of Parkinson's disease, but how these inclusions are formed and how this links to disease is poorly understood. We have developed a C. elegans model that makes it possible to monitor, in living animals, the formation o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265412/ https://ncbi.nlm.nih.gov/pubmed/18369446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000027 |
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