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Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms

Various age-related neurodegenerative diseases, including Parkinson's disease, polyglutamine expansion diseases and Alzheimer's disease, are associated with the accumulation of misfolded proteins in aggregates in the brain. How and why these proteins form aggregates and cause disease is st...

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Detalhes bibliográficos
Main Authors: van Ham, Tjakko J, Breitling, Rainer, Swertz, Morris A, Nollen, Ellen A A
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378155/
https://ncbi.nlm.nih.gov/pubmed/20049741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.200900051
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