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Regulation of Mih1/Cdc25 by protein phosphatase 2A and casein kinase 1

The Cdc25 phosphatase promotes entry into mitosis by removing cyclin-dependent kinase 1 (Cdk1) inhibitory phosphorylation. Previous work suggested that Cdc25 is activated by Cdk1 in a positive feedback loop promoting entry into mitosis; however, it has remained unclear how the feedback loop is initi...

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Hlavní autoři: Pal, Gayatri, Paraz, Maria T.Z., Kellogg, Douglas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265403/
https://ncbi.nlm.nih.gov/pubmed/18316413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200711014
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