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Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes

CD22 is a B cell-restricted glycoprotein involved in signal transduction and modulation of cellular activation. It is also an I-type lectin (now designated Siglec-2), whose extracellular domain can specifically recognize α2–6-linked sialic acid (Sia) residues. This activity is postulated to mediate...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Razi, Nahid, Varki, Ajit
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7469
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