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Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes
CD22 is a B cell-restricted glycoprotein involved in signal transduction and modulation of cellular activation. It is also an I-type lectin (now designated Siglec-2), whose extracellular domain can specifically recognize α2–6-linked sialic acid (Sia) residues. This activity is postulated to mediate...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
1998
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22653/ https://ncbi.nlm.nih.gov/pubmed/9636173 |
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