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Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes

CD22 is a B cell-restricted glycoprotein involved in signal transduction and modulation of cellular activation. It is also an I-type lectin (now designated Siglec-2), whose extracellular domain can specifically recognize α2–6-linked sialic acid (Sia) residues. This activity is postulated to mediate...

詳細記述

保存先:
書誌詳細
主要な著者: Razi, Nahid, Varki, Ajit
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC22653/
https://ncbi.nlm.nih.gov/pubmed/9636173
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