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Both ovarian hormones estrogen and progesterone are necessary for hormonal mammary carcinogenesis in ovariectomized ACI rats

August–Copenhagen–Irish (ACI) rats are unique in that the ovary-intact females develop high incidence of mammary cancers induced solely by hormones upon prolonged exposure to high levels of estrogen alone. Studies have also shown that such prolonged exposure to high-dose estrogen results in human-li...

詳細記述

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書誌詳細
主要な著者: Blank, Edward W., Wong, Po-Yin, Lakshmanaswamy, Rajkumar, Guzman, Raphael, Nandi, Satyabrata
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265202/
https://ncbi.nlm.nih.gov/pubmed/18299580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710535105
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