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PD-1 deficiency reveals various tissue-specific autoimmunity by H-2(b) and dose-dependent requirement of H-2(g7) for diabetes in NOD mice

Although many autoimmune diseases are associated with particular HLA/H-2 haplotypes, the mechanisms through which specific HLA/H-2 haplotypes afford autoimmune susceptibility remain enigmatic. Here, we analyzed the effects of the diabetes-associated (H-2(g7)) and an antidiabetogenic (H-2(b)) H-2 hap...

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Bibliographic Details
Main Authors: Yoshida, Taku, Jiang, Fang, Honjo, Tasuku, Okazaki, Taku
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265199/
https://ncbi.nlm.nih.gov/pubmed/18299579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710951105
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