Mesenchymal–epithelial interactions involving epiregulin in tuberous sclerosis complex hamartomas

Patients with tuberous sclerosis complex (TSC) develop hamartomas containing biallelic inactivating mutations in either TSC1 or TSC2, resulting in mammalian target of rapamycin (mTOR) activation. Hamartomas overgrow epithelial and mesenchymal cells in TSC skin. The pathogenetic mechanisms for these...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Li, Shaowei, Takeuchi, Fumiko, Wang, Ji-an, Fan, Qingyuan, Komurasaki, Toshi, Billings, Eric M., Pacheco-Rodriguez, Gustavo, Moss, Joel, Darling, Thomas N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265180/
https://ncbi.nlm.nih.gov/pubmed/18292222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712397105
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars