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Defining genetic interaction

Sometimes mutations in two genes produce a phenotype that is surprising in light of each mutation's individual effects. This phenomenon, which defines genetic interaction, can reveal functional relationships between genes and pathways. For example, double mutants with surprisingly slow growth d...

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Bibliografiske detaljer
Main Authors: Mani, Ramamurthy, St.Onge, Robert P., Hartman, John L., Giaever, Guri, Roth, Frederick P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265146/
https://ncbi.nlm.nih.gov/pubmed/18305163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712255105
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