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The Rap–RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues
The GTP-binding protein Rap1 regulates integrin-mediated and other cell adhesion processes. Unlike most other Ras-related proteins, it contains a threonine in switch II instead of a glutamine (Gln61 in Ras), a residue crucial for the GTPase reaction of most G proteins. Furthermore, unlike most other...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265111/ https://ncbi.nlm.nih.gov/pubmed/18309292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.30 |
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