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Structure and topology of the non-amyloid-β component fragment of human α-synuclein bound to micelles: Implications for the aggregation process

Human α-synuclein is a small soluble protein abundantly expressed in neurons. It represents the principal constituent of Lewy bodies, the main neuropathological characteristic of Parkinson's disease. The fragment corresponding to the region 61–95 of the protein, originally termed NAC (non-amylo...

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Détails bibliographiques
Auteurs principaux: Bisaglia, Marco, Trolio, Alessandra, Bellanda, Massimo, Bergantino, Elisabetta, Bubacco, Luigi, Mammi, Stefano
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265094/
https://ncbi.nlm.nih.gov/pubmed/16731975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052048706
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