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Structure and topology of the non-amyloid-β component fragment of human α-synuclein bound to micelles: Implications for the aggregation process

Human α-synuclein is a small soluble protein abundantly expressed in neurons. It represents the principal constituent of Lewy bodies, the main neuropathological characteristic of Parkinson's disease. The fragment corresponding to the region 61–95 of the protein, originally termed NAC (non-amylo...

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Detalhes bibliográficos
Main Authors: Bisaglia, Marco, Trolio, Alessandra, Bellanda, Massimo, Bergantino, Elisabetta, Bubacco, Luigi, Mammi, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265094/
https://ncbi.nlm.nih.gov/pubmed/16731975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052048706
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