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Structure and topology of the non-amyloid-β component fragment of human α-synuclein bound to micelles: Implications for the aggregation process

Human α-synuclein is a small soluble protein abundantly expressed in neurons. It represents the principal constituent of Lewy bodies, the main neuropathological characteristic of Parkinson's disease. The fragment corresponding to the region 61–95 of the protein, originally termed NAC (non-amylo...

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Bibliographic Details
Main Authors: Bisaglia, Marco, Trolio, Alessandra, Bellanda, Massimo, Bergantino, Elisabetta, Bubacco, Luigi, Mammi, Stefano
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265094/
https://ncbi.nlm.nih.gov/pubmed/16731975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052048706
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