Structural basis of an embryonically lethal single Ala → Thr mutation in the vnd/NK-2 homeodomain

The structural and DNA binding behavior is described for an analog of the vnd/NK-2 homeodomain, which contains a single amino acid residue alanine to threonine replacement in position 35 of the homeodomain. Multidimensional nuclear magnetic resonance, circular dichroism, and electrophoretic gel reta...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Xiang, Bosong, Weiler, Solly, Nirenberg, Marshall, Ferretti, James A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1998
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7412
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