Structural basis of an embryonically lethal single Ala → Thr mutation in the vnd/NK-2 homeodomain
The structural and DNA binding behavior is described for an analog of the vnd/NK-2 homeodomain, which contains a single amino acid residue alanine to threonine replacement in position 35 of the homeodomain. Multidimensional nuclear magnetic resonance, circular dichroism, and electrophoretic gel reta...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7412 |
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