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Adeno-associated virus–targeted disruption of the CFTR gene in cloned ferrets
Somatic cell gene targeting combined with nuclear transfer cloning presents tremendous potential for the creation of new, large-animal models of human diseases. Mouse disease models often fail to reproduce human phenotypes, underscoring the need for the generation and study of alternative disease mo...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2263147/ https://ncbi.nlm.nih.gov/pubmed/18324338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34599 |
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