Expression of Toll/IL-1R Domain-Containing Adaptor Protein (TIRAP) is detrimental to primary clearance of Salmonella and is not required for the generation of protective immunity

Salmonella infection triggers activation of innate immune cells through the interaction of bacterial products with Toll-like Receptors (TLRs). Toll/IL-1 domain-containing adaptor protein (TIRAP) is an adaptor protein involved in downstream signaling through TLR-1, TLR-2, TLR-4, and TLR-6. We examine...

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Bibliographic Details
Main Authors: Jerke, Stu, Srinivasan, Aparna, McSorley, Stephen J.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263078/
https://ncbi.nlm.nih.gov/pubmed/18096248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2007.11.007
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