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Culling of activated CD4 T cells during typhoid is driven by Salmonella virulence genes

Pathogen-specific CD4 T cells are activated within a few hours of oral Salmonella infection and are essential for protective immunity. However, CD4 T cells do not participate in bacterial clearance until several weeks after infection, suggesting that Salmonella can inhibit or evade CD4 T cells that...

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Detalhes bibliográficos
Main Authors: Srinivasan, Aparna, Nanton, Minelva, Griffin, Amanda, McSorley, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731968/
https://ncbi.nlm.nih.gov/pubmed/19494308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900382
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