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Innate Immune Activation during Salmonella Infection Initiates Extramedullary Erythropoiesis and Splenomegaly

Systemic Salmonella infection commonly induces prolonged splenomegaly in murine or human hosts. Although this increase in splenic cellularity is often assumed to be due to the recruitment and expansion of leukocytes, the actual cause of splenomegaly remains unclear. We monitored spleen cell populati...

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Detalhes bibliográficos
Main Authors: Jackson, Amy, Nanton, Minelva R., O’Donnell, Hope, Akue, Adovi D., McSorley, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137927/
https://ncbi.nlm.nih.gov/pubmed/20952675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001198
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