The Ubiquitin-like Protein PLIC-2 Is a Negative Regulator of G Protein-coupled Receptor Endocytosis

The activity of many signaling receptors is regulated by their endocytosis via clathrin-coated pits (CCPs). For G protein-coupled receptors (GPCRs), recruitment of the adaptor protein arrestin to activated receptors is thought to be sufficient to drive GPCR clustering in CCPs and subsequent endocyto...

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Main Authors: N'Diaye, Elsa-Noah, Hanyaloglu, Aylin C., Kajihara, Kimberly K., Puthenveedu, Manojkumar A., Wu, Ping, von Zastrow, Mark, Brown, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262968/
https://ncbi.nlm.nih.gov/pubmed/18199683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-08-0775
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