Correlation of immunogenicities and in vitro expression levels of recombinant modified vaccinia virus Ankara HIV vaccines

The purpose of the present study was to correlate the in vitro level of HIV Env expression by recombinant modified vaccinia virus Ankara (rMVA) with immunogenicity in mice. A 5-fold difference in Env synthesis was achieved at the translational level by the presence or absence of an out-of-frame init...

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Main Authors: Wyatt, Linda S., Earl, Patricia L., Vogt, Jennifer, Eller, Leigh Anne, Chandran, Dev, Liu, Jinyan, Robinson, Harriet L., Moss, Bernard
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262837/
https://ncbi.nlm.nih.gov/pubmed/18155813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.11.036
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