Correlation of immunogenicities and in vitro expression levels of recombinant modified vaccinia virus Ankara HIV vaccines

The purpose of the present study was to correlate the in vitro level of HIV Env expression by recombinant modified vaccinia virus Ankara (rMVA) with immunogenicity in mice. A 5-fold difference in Env synthesis was achieved at the translational level by the presence or absence of an out-of-frame init...

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Autores principales: Wyatt, Linda S., Earl, Patricia L., Vogt, Jennifer, Eller, Leigh Anne, Chandran, Dev, Liu, Jinyan, Robinson, Harriet L., Moss, Bernard
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262837/
https://ncbi.nlm.nih.gov/pubmed/18155813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.11.036
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