Phase 1 Safety and Immunogenicity Testing of DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-like Particles

Background. Recombinant DNA and modified vaccinia virus Ankara (rMVA) vaccines represent a promising approach to an HIV/AIDS vaccine. This Phase 1 clinical trial compared the safety and immunogenicity of a rMVA vaccine administered with and without DNA vaccine priming Methods. GeoVax pGA2/JS7 DNA (D...

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Detalhes bibliográficos
Main Authors: Goepfert, Paul A., Elizaga, Marnie L., Sato, Alicia, Qin, Li, Cardinali, Massimo, Hay, Christine M., Hural, John, DeRosa, Stephen C., DeFawe, Olivier D., Tomaras, Georgia D., Montefiori, David C., Xu, Yongxian, Lai, Lilin, Kalams, Spyros A., Baden, Lindsey R., Frey, Sharon E., Blattner, William A., Wyatt, Linda S., Moss, Bernard, Robinson, Harriet L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072720/
https://ncbi.nlm.nih.gov/pubmed/21282192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq105
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