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Ligand-Independent Activation of Androgen Receptors by Rho GTPase Signaling in Prostate Cancer

Prostate cancer invariably recurs after androgen deprivation therapy. Growth of this recurrent/androgen-independent form of prostate cancer may be due to increased androgen receptor (AR) transcriptional activity in the absence of androgen. This ligand-independent AR activation is promoted by some gr...

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Autori principali: Lyons, Leah S., Rao, Shuyun, Balkan, Wayne, Faysal, Joanne, Maiorino, Carol A., Burnstein, Kerry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262175/
https://ncbi.nlm.nih.gov/pubmed/18079321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0158
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