Receptor Activator of Nuclear Factor-κB Ligand-Induced Nuclear Factor of Activated T Cells (C1) Autoregulates Its Own Expression in Osteoclasts and Mediates the Up-Regulation of Tartrate-Resistant Acid Phosphatase

Osteoclasts are large multinucleated, bone-resorbing cells derived from hematopoietic precursors in response to receptor activator of nuclear factor-κB ligand (RANKL). RANKL activates a number of signal transduction pathways, which stimulate, in turn, a series of specific transcription factors that...

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Bibliographic Details
Main Authors: Fretz, Jackie A., Shevde, Nirupama K., Singh, Sujay, Darnay, Bryant G., Pike, J. Wesley
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262172/
https://ncbi.nlm.nih.gov/pubmed/18063694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0333
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