Modulation of in Situ Estrogen Synthesis by Proline-, Glutamic Acid-, and Leucine-Rich Protein-1: Potential Estrogen Receptor Autocrine Signaling Loop in Breast Cancer Cells

In situ estrogen synthesis is implicated in tumor cell proliferation through autocrine or paracrine mechanisms especially in postmenopausal women. Several recent studies demonstrated activity of aromatase, an enzyme that plays a critical role in estrogen synthesis in breast tumors. Proline-, glutami...

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Autori principali: Rajhans, Rajib, Nair, Hareesh B., Nair, Sujit S., Cortez, Valerie, Ikuko, Kijima, Kirma, Nameer B., Zhou, Dujin, Holden, Alan E., Brann, Darrell W, Chen, Shiuan, Tekmal, Rajeshwar Rao, Vadlamudi, Ratna K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262166/
https://ncbi.nlm.nih.gov/pubmed/18079323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0350
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