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HER-2/neu × Aromatase Double Transgenic Mice Model: The Effects of Aromatase Overexpression on Mammary Tumorigenesis

A majority of breast cancers are hormone-responsive, and require estrogen for growth, and respond to hormonal therapy that blocks estrogen receptor action. Breast tumors with low levels of or completely lacking estrogen receptor fail to respond to antiestrogen therapy yet require estrogen for tumor...

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Detalhes bibliográficos
Main Authors: Tekmal, Rajeshwar Rao, Nair, Hareesh B., Perla, Rao P., Kirma, Nameer
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084397/
https://ncbi.nlm.nih.gov/pubmed/17604617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.05.009
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