Modulation of in Situ Estrogen Synthesis by Proline-, Glutamic Acid-, and Leucine-Rich Protein-1: Potential Estrogen Receptor Autocrine Signaling Loop in Breast Cancer Cells

In situ estrogen synthesis is implicated in tumor cell proliferation through autocrine or paracrine mechanisms especially in postmenopausal women. Several recent studies demonstrated activity of aromatase, an enzyme that plays a critical role in estrogen synthesis in breast tumors. Proline-, glutami...

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Détails bibliographiques
Auteurs principaux: Rajhans, Rajib, Nair, Hareesh B., Nair, Sujit S., Cortez, Valerie, Ikuko, Kijima, Kirma, Nameer B., Zhou, Dujin, Holden, Alan E., Brann, Darrell W, Chen, Shiuan, Tekmal, Rajeshwar Rao, Vadlamudi, Ratna K.
Format: Artigo
Langue:Inglês
Publié: The Endocrine Society 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262166/
https://ncbi.nlm.nih.gov/pubmed/18079323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0350
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