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The Impact of the Human DNA Topoisomerase II C-Terminal Domain on Activity
BACKGROUND: Type II DNA topoisomerases (topos) are essential enzymes needed for the resolution of topological problems that occur during DNA metabolic processes. Topos carry out an ATP-dependent strand passage reaction whereby one double helix is passed through a transient break in another. Humans h...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262138/ https://ncbi.nlm.nih.gov/pubmed/18335031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001754 |
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