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Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC α-subunit in mice

An epithelial Na(+) channel (ENaC) is expressed in taste cells and may be involved in the salt taste transduction. ENaC activity is blocked by amiloride, which in several mammalian species also inhibits taste responses to NaCl. In mice, lingual application of amiloride inhibits NaCl responses in the...

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Main Authors: Shigemura, Noriatsu, Ohkuri, Tadahiro, Sadamitsu, Chiharu, Yasumatsu, Keiko, Yoshida, Ryusuke, Beauchamp, Gary K., Bachmanov, Alexander A., Ninomiya, Yuzo
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262045/
https://ncbi.nlm.nih.gov/pubmed/17977920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00420.2007
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