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Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC α-subunit in mice

An epithelial Na(+) channel (ENaC) is expressed in taste cells and may be involved in the salt taste transduction. ENaC activity is blocked by amiloride, which in several mammalian species also inhibits taste responses to NaCl. In mice, lingual application of amiloride inhibits NaCl responses in the...

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Autors principals: Shigemura, Noriatsu, Ohkuri, Tadahiro, Sadamitsu, Chiharu, Yasumatsu, Keiko, Yoshida, Ryusuke, Beauchamp, Gary K., Bachmanov, Alexander A., Ninomiya, Yuzo
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262045/
https://ncbi.nlm.nih.gov/pubmed/17977920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00420.2007
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