The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

Mutations in the gene autoimmune regulator (AIRE) cause autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells, where it promotes the expression of tissue-restricted antigens. By the combined use of biochemical and biophysical methods,...

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Bibliografiske detaljer
Main Authors: Org, Tõnis, Chignola, Francesca, Hetényi, Csaba, Gaetani, Massimiliano, Rebane, Ana, Liiv, Ingrid, Maran, Uko, Mollica, Luca, Bottomley, Matthew J, Musco, Giovanna, Peterson, Pärt
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2261226/
https://ncbi.nlm.nih.gov/pubmed/18292755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.11
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