The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

Mutations in the gene autoimmune regulator (AIRE) cause autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells, where it promotes the expression of tissue-restricted antigens. By the combined use of biochemical and biophysical methods,...

詳細記述

保存先:
書誌詳細
主要な著者: Org, Tõnis, Chignola, Francesca, Hetényi, Csaba, Gaetani, Massimiliano, Rebane, Ana, Liiv, Ingrid, Maran, Uko, Mollica, Luca, Bottomley, Matthew J, Musco, Giovanna, Peterson, Pärt
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2008
主題:
Scientific Report
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2261226/
https://ncbi.nlm.nih.gov/pubmed/18292755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.11
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