Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(ε-caprolactone) micelles of rapamycin

PURPOSE: To determine the pharmacokinetics, tissue, and blood distribution of rapamycin PEG-block-poly(ε-caprolactone) (PEG-b-PCL) micelle formulations with and without the addition of α-tocopherol compared to control rapamycin in Tween 80/PEG 400/N,N-dimethylacetamide (DMA) (7:64:29). METHODS: Rapa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yáñez, Jaime A., Forrest, M. Laird, Ohgami, Yusuke, Kwon, Glen S., Davies, Neal M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259393/
https://ncbi.nlm.nih.gov/pubmed/17393166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-007-0458-z
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