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SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis

SOX transcription factors are essential for embryonic development and play critical roles in cell fate determination, differentiation and proliferation. We previously reported that the SOX2 protein is expressed in normal gastric mucosae but downregulated in some human gastric carcinomas. To clarify...

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書誌詳細
主要な著者: Otsubo, T, Akiyama, Y, Yanagihara, K, Yuasa, Y
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259184/
https://ncbi.nlm.nih.gov/pubmed/18268498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604193
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