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SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis

SOX transcription factors are essential for embryonic development and play critical roles in cell fate determination, differentiation and proliferation. We previously reported that the SOX2 protein is expressed in normal gastric mucosae but downregulated in some human gastric carcinomas. To clarify...

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Библиографические подробности
Главные авторы: Otsubo, T, Akiyama, Y, Yanagihara, K, Yuasa, Y
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259184/
https://ncbi.nlm.nih.gov/pubmed/18268498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604193
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