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Human Immunodeficiency Virus Type 1 Vpr Induces Cell Cycle G(2) Arrest through Srk1/MK2-Mediated Phosphorylation of Cdc25

Human immunodeficiency virus type 1 (HIV-1) Vpr induces cell cycle G(2) arrest in fission yeast (Schizosaccharomyces pombe) and mammalian cells, suggesting the cellular pathway(s) targeted by Vpr is conserved among eukaryotes. Our previous studies in fission yeast demonstrated that Vpr induces G(2)...

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Detalles Bibliográficos
Main Authors: Huard, Sylvain, Elder, Robert T., Liang, Dong, Li, Ge, Zhao, Richard Y.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259012/
https://ncbi.nlm.nih.gov/pubmed/18160429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01098-07
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