Human Immunodeficiency Virus Type 1 Vpr Induces Cell Cycle G(2) Arrest through Srk1/MK2-Mediated Phosphorylation of Cdc25

Human immunodeficiency virus type 1 (HIV-1) Vpr induces cell cycle G(2) arrest in fission yeast (Schizosaccharomyces pombe) and mammalian cells, suggesting the cellular pathway(s) targeted by Vpr is conserved among eukaryotes. Our previous studies in fission yeast demonstrated that Vpr induces G(2)...

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Bibliographische Detailangaben
Hauptverfasser: Huard, Sylvain, Elder, Robert T., Liang, Dong, Li, Ge, Zhao, Richard Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259012/
https://ncbi.nlm.nih.gov/pubmed/18160429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01098-07
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